Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Avianca

The cheapest airline(s) flying from Mexico City to Panama City is Avianca.

  • Avianca Avianca
  • Copa Airlines Copa Airlines
  • United Airlines United Airlines
  • American Airlines American Airlines
  • British Airways British Airways
Cheapest Month February

Travel Period: December 2024 - November 2025

The cheapest month(s) to fly from Mexico City to Panama City is February.

  • Dec 2024
  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
Cheapest Day of the Week Thursday

The cheapest day(s) of the week to fly from Mexico City to Panama City is Thursday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Sat, 2 Nov, 2024

  • Time Earliest
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    • Earliest
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    • Earliest
    • Latest
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  • Availability
    • M
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  • 01:20 MEX
    06:01 PTY
    3Hrs, 41m Direct
  • MEXMexico City Juarez International Airport 01:20 - PTY 06:01 3h 41m Direct
  • MEXMexico City Juarez International Airport 01:20
  • PTYPanama City Tocumen International Airport 06:01
  • 3h 41m
  • Direct
  • Copa Airlines (CM 149)Boeing 737 800
  • Copa Airlines (CM 149)
    • M
    • T
    • W
    • T
    • F
    • S
    • S
  • Boeing 737 800
  • 02:00 MEX
    06:41 PTY
    3Hrs, 41m Direct
  • MEXMexico City Juarez International Airport 02:00 - PTY 06:41 3h 41m Direct
  • MEXMexico City Juarez International Airport 02:00
  • PTYPanama City Tocumen International Airport 06:41
  • 3h 41m
  • Direct
  • Copa Airlines (CM 857)Boeing 737 800
  • Copa Airlines (CM 857)
    • -
    • T
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    • T
    • F
    • S
    • S
  • Boeing 737 800
  • 02:00 MEX
    06:41 PTY
    3Hrs, 41m Direct
  • MEXMexico City Juarez International Airport 02:00 - PTY 06:41 3h 41m Direct
  • MEXMexico City Juarez International Airport 02:00
  • PTYPanama City Tocumen International Airport 06:41
  • 3h 41m
  • Direct
  • Copa Airlines (CM 857)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 857)
    • M
    • -
    • -
    • -
    • -
    • -
    • -
  • Boeing 737 Max 9 Passenger
  • 05:55 MEX
    10:41 PTY
    3Hrs, 46m Direct
  • MEXMexico City Juarez International Airport 05:55 - PTY 10:41 3h 46m Direct
  • MEXMexico City Juarez International Airport 05:55
  • PTYPanama City Tocumen International Airport 10:41
  • 3h 46m
  • Direct
  • Copa Airlines (CM 195)Boeing 737 800
  • Copa Airlines (CM 195)
    • M
    • T
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    • T
    • F
    • S
    • -
  • Boeing 737 800
  • 05:55 MEX
    10:41 PTY
    3Hrs, 46m Direct
  • MEXMexico City Juarez International Airport 05:55 - PTY 10:41 3h 46m Direct
  • MEXMexico City Juarez International Airport 05:55
  • PTYPanama City Tocumen International Airport 10:41
  • 3h 46m
  • Direct
  • Copa Airlines (CM 195)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 195)
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • Boeing 737 Max 9 Passenger
  • 09:25 MEX
    14:15 PTY
    3Hrs, 50m Direct
  • MEXMexico City Juarez International Airport 09:25 - PTY 14:15 3h 50m Direct
  • MEXMexico City Juarez International Airport 09:25
  • PTYPanama City Tocumen International Airport 14:15
  • 3h 50m
  • Direct
  • Copa Airlines (CM 137)Boeing 737 800
  • Copa Airlines (CM 137)
    • M
    • T
    • W
    • T
    • F
    • S
    • S
  • Boeing 737 800
  • 13:10 MEX
    17:55 PTY
    3Hrs, 45m Direct
  • MEXMexico City Juarez International Airport 13:10 - PTY 17:55 3h 45m Direct
  • MEXMexico City Juarez International Airport 13:10
  • PTYPanama City Tocumen International Airport 17:55
  • 3h 45m
  • Direct
  • Copa Airlines (CM 121)Boeing 737 800
  • Copa Airlines (CM 121)
    • M
    • T
    • W
    • T
    • F
    • S
    • S
  • Boeing 737 800
  • 14:46 NLU
    19:43 PTY
    3Hrs, 57m Direct
  • NLU 14:46 - PTY 19:43 3h 57m Direct
  • NLU 14:46
  • PTYPanama City Tocumen International Airport 19:43
  • 3h 57m
  • Direct
  • Copa Airlines (CM 117)Boeing 737 800
  • Copa Airlines (CM 117)
    • M
    • -
    • -
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    • -
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    • -
  • Boeing 737 800
  • 15:30 MEX
    20:16 PTY
    3Hrs, 46m Direct
  • MEXMexico City Juarez International Airport 15:30 - PTY 20:16 3h 46m Direct
  • MEXMexico City Juarez International Airport 15:30
  • PTYPanama City Tocumen International Airport 20:16
  • 3h 46m
  • Direct
  • Copa Airlines (CM 135)Boeing 737 800
  • Copa Airlines (CM 135)
    • M
    • T
    • W
    • T
    • F
    • S
    • S
  • Boeing 737 800
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What’s the fastest flight time from Mexico City to Panama City?

The fastest flight time for direct flights from Mexico City to Panama City is 3 hours 41 minutes. Check latest flight schedules & prices on Wego.

What’s the most popular airline flying from Mexico City to Panama City?

The most popular airline flying from Mexico City to Panama City is Avianca. Find the latest flight deals on Wego.

How far is Panama City from Mexico City?

The flight distance between Mexico City and Panama City is 2409km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 01:20. The last flight of the day departs at 01:20. See the full list of flight times on Wego.

How many airlines offer direct flights from Mexico City to Panama City?

There are 1 airlines that offer direct flights from Mexico City to Panama City. Find out the list of airlines on Wego.